Scientific Manager

Embark on a transformative journey with our client, a powerhouse dedicated to forging a world unburdened by disease. Driven by the pursuit of novel and superior strategies for disease prevention, interception, treatment, and cure, this visionary organization unites exceptional intellects and groundbreaking scientific endeavors. The organisation stands as a testament to collaborative innovation, working hand-in-hand with global partners to safeguard the health of all. Within this dynamic environment, the Cell and Gene Therapy Analytics (CGTA) team, a vibrant collective of 22 members, operates at the forefront of innovation within Cell and Gene Therapies Analytical Development (CGT AD) Leiden. Their critical mission is the development of sophisticated analytical methods designed to meticulously characterize the company's cutting-edge viral vector products, including those based on Adenovirus, AAV, lentivirus, and RNA. Leveraging a formidable arsenal of molecular, biological, biophysical, and separation-based technologies, the CGTA team diligently assesses the quantity, potency, purity, and identity of these vital products. They serve as a linchpin, bridging the crucial interfaces between process development, the quality unit, and regulatory authorities, ensuring the highest standards of scientific rigor and product integrity. A Unique Opportunity for a Scientific Manager to Lead and Innovate Our client seeks a visionary Scientific Manager to lead a complementary team focused on developing state-of-the-art biophysical and separation technology-based methods. This role demands a natural scientific mentor with an exceptional aptitude for identifying and nurturing talent within the team. The ideal candidate will act as a pivotal technical analytical lead, significantly bolstering the product development strategy, with a particular emphasis on lipid nanoparticle (LNP)-based products. This individual will be instrumental in actively disseminating deep technical expertise in biophysical and separation-based technologies, including advanced techniques such as liquid chromatography (LC), light scattering, and capillary electrophoresis (CE). A core responsibility will be to champion the selection and seamless implementation of the most effective technologies to meet evolving analytical challenges. Furthermore, this role calls for a proactive approach to managing the entire lifecycle of analytical methods, from early-stage development utilizing Quality by Design (QbD) principles, through to validation for product release and characterization. A commitment to a lean mentality, driving continuous optimization and efficiency, will be paramount. The successful candidate will thrive in a multidisciplinary setting, demonstrating strong collaborative capabilities to foster synergy with scientists across various teams. A key facet of this leadership position involves taking ownership as an author or reviewer in the meticulous preparation of presentations, reports, and essential documents required for regulatory filings and patent applications. Join our client and be a driving force in shaping the future of medicine.